Paroxysmal nocturnal hemoglobinuria
A rare acquired hematologic disorder characterized by hemolytic anemia, dark-colored urine due to the release of hemoglobin in the blood, and thrombosis. The episodes of hemolysis tend to occur at night. It is caused by a somatic mutation in the glycosylphosphatidylinositol biosynthesis gene.
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Yashoda Hospital
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Sir Ganga Ram Hospital
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PGIMER, Chandigarh
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