Gorlin syndrome

An autosomal dominant genetic syndrome caused by abnormalities in the PTCH gene. It is characterized by multiple basal cell carcinomas at a young age, odontogenic keratocysts, and skeletal defects (bifurcated and splayed ribs, fusion of vertebrae, spinal bifida). Patients with this syndrome may also develop medulloblastomas and ovarian fibromas.

Disease Alternative Name

gorlin-goltz syndrome

nevoid basal cell carcinoma syndrome

basal cell nevus syndrome

nevoid basal cell cancer syndrome

multiple basal cell carcinomas

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Samarth Goyal

MBBS Student

Which of the following syndrome is not commonly associated with basal cell carcinoma? 1)gorlin syndrome 2)xeroserma pigementosum 3)bazex syndrome 4)Cowden syndrome

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Dr. Jamil Ahmed

Ayurveda

White Spots On Nail Certain nail changes are specific for various dermatological disorders. In addition, examination of nails may also provide an insight into some systemic manifestations in the form subtle as well as specific changes. T...See More

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