Glioblastoma
The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. It may develop from diffuse astrocytoma WHO grade II or anaplastic astrocytoma (secondary glioblastoma, IDH-mutant), but more frequently, it manifests after a short clinical history de novo, without evidence of a less malignant precursor lesion (primary glioblastoma, IDH- wildtype). (Adapted from WHO)
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Thanks for the answers. Admitted and received 2doses of metyl pred, Iv 1gr each. Father of pt is also a doctor. Discussed with others . Majority suggested Stereotactic biopsy which is not available here and hence transferred to near b...
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Brain edema raised ICP and 2ndary vascular compromise and PCA infarction. Kernohan notch - a radiological findings due to midline shift due to mass effect resulting in compression of contralateral cerebral crust by tentorium cerebelli resu...
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It is high grade glioma, life expectancy is about 1-1.5 yr. Biopsy with chemo/ radio therapy can be given. If deteriorate decompression can be done. Continue antiedema and antiepileptic. Ayushman can be used anywhere in India.
Recent Cases of Glioblastoma
Browse recently discussed Glioblastoma cases by specialistsTop Cases of Glioblastoma
Selected by editors, top cases are known for unique problem or best solutionTop Glioblastoma Doctors on Curofy
Top doctors who continously share their opinions on GlioblastomaKerala Institute of Medical Sciences
Professor and Senior Consultant Neurology
Medical College Thiruvananthapuram
MBBS,MD (Med) ,DM(Neurology),DNB(Neurology), FAAN(Fellow of American Academy of Neurology)
Medical Component OfHCM
Remained Incharge Medical Officer with Hon'Ble C.M of J and K for More Than 20 Years from Jan 2000 To October 2020
Govt. Medical College, Jammu
M.S (General Surgery )
20 Years of Teaching To Both UGs & PGs
As Assistant, Associate & Professor
Gandhi Medical College, Dr. NTRUHS
MD Pathology
Anand Hospital
Neuro Intensive Care
Zhengzhou University
MBBS
PHC Bichpuri and ESI Dispensary Chippitola Agra & SN Medical College Agra & Fatehgarh
Medical Officer Incharge
SN Medical College, Agra
DA
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Which of the drugs do you recommend for symptomatic management of fever and pain in children?
Doc Insights10 Likes27 AnswersWith advancements in medical technology, there will be a diminishing in the reliance on traditional stethoscopes. Expert predicts the analogue version—where doctors listen to the heart & lungs by placing a stethoscope probe in their ears & the chest piece on the patient—will face formidable competition from electronic, digital, & now AI-powered versions. AI supported stethoscope, record, & analyse sounds graphically & be transmitted via Bluetooth or an app. Do these advancements mean that the stethoscope is redundant as the first point of contact with a patient in coming time. What do you think about it?
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Medi Facts3 Likes5 Answers Please share your overall clinical experience with the Ibuprofen + Paracetamol combination in treating Paediatric Fever and pain?
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A 57 yrs old male patient c/o sudden vision loss/left side weakness/agitated/fever bodyache *Chief Complaints* Sudden vision loss Left side weakness Unable to walk Agitated urge to pee/poop but nothing comes out when he go Bodyache *History* CVA with left hemisphere 3 yrs back K/c/o HTN/DM *Vitals* BP 150/80 Pulse 68 Spo2 98 *Physical Examination* B/L Pupils dilated Left side weakness Chest -B/L clear P/A- soft no any tenderness or distension CNS -Alert and aware Genitals -Normal *Investigations* Attached *Diagnosis* CVA with HTN/DM ?TIA/Retinal detachment *Management* Medically conservative Kindly suggest
Dr. Manoj Kumar0 Like3 Answers
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