Familial polyposis coli

An autosomal dominant disorder, characterized by the presence of multiple adenomas in the colon and rectum. It is caused by a germline mutation in the adenomatous polyposis coli (APC) gene which is located on the long arm of chromosome 5. The adenomas are most often tubular, and they have the tendency to progress to adenocarcinoma. They can occur throughout the colon, but they tend to concentrate in the rectum and sigmoid colon. The colorectal adenomas are detected during endoscopic examination between the age of 10 and 20 years. The adenomas increase in size and numbers with age, and there is usually progression of one or more adenomas to adenocarcinoma. The mean age of development of adenocarcinoma is about 40 years. Signs include rectal bleeding and mucousy diarrhea.

Disease Alternative Name

familial adenomatous polyposis
adenomatous polyposis coli
familial adenomatous polyposis syndrome
polyposis coli
hereditary adenomatous polyposis coli
familial polyposis
apc - adenomatous polyposis coli
fap
familial adenomatous polyposis coli
MainRecentTopDoctors

Recent Cases of Familial polyposis coli

Browse recently discussed Familial polyposis coli cases by specialists

Top Familial polyposis coli Doctors on Curofy

Top doctors who continously share their opinions on Familial polyposis coli
Morbi
1236 followers

Self Emploid(private Clinic)

Morbi

Shri M P Shah Medical College Jamnagar

M B B S

User Languages
Speaks English
Pondicherry
13 followers
User Languages
Speaks English
Visakhapatnam
318 followers

Anil Neerukonda Institute of Technology & Sciences

3yrs

Konaseema Inst. of Medical Sciences Research Foundation

mbbs

User Languages
Speaks English
Guwahati
98 followers

Assam Medical College, Gauhati Medical College

Assistant Professor

Gauhati Medical College

MBBS,MD , PhD

User Languages
Speaks Assamese, Bengali, English, Hindi
Hyderabad
133 followers

NIMS

Associate Professor

Osmania Medical College

MD Pathology

User Languages
Speaks English