Eosinophilic granuloma

A clinical variant of Langerhans cell histiocytosis characterized by unifocal involvement of a bone (most often), skin, or lung. Patients are usually older children or adults usually presenting with a lytic bone lesion. The etiology is unknown. Morphologically, eosinophilic granuloma is characterized by the presence of Langerhans cells in a characteristic milieu which includes histiocytes, eosinophils, neutrophils, and small, mature lymphocytes.

Disease Alternative Name

eosinophilic xanthomatous granuloma

monostotic langerhans cell histiocytosis

unifocal langerhans cell histiocytosis

chronic unifocal langerhans cell histiocytosis

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Recent Cases of Eosinophilic granuloma

Browse recently discussed Eosinophilic granuloma cases by specialists

Dr. Anupam Singh

Pathology

9y F, intervertebral tissue..... kindly give ur opinions....... (there r two differentials given in clinician's paper ...See More

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Dr. Avinash Kr Gowda

Veterinary

Treated with cephalexin for 7 days chlorhex spray oint.mupirocin tab wysalone but not reduced Pododermatitis?? or e...See More

468 Views

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Top Cases of Eosinophilic granuloma

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Dr. Ila Jain

Pathology

1. Langerhans cell histiocytosis It is a spectrum of proliferation of immature dendritic cells called langerhans cell. 2. The most common mutation is activating valine to glutamate substitution at residue 600 in BRAF. 3. Clinically man...See More

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