Minimal change disease

A glomerular disorder characterized by the electron microscopic finding of loss of podocyte foot processes. Light microscopic examination does not show glomerular changes. Patients present with proteinuria and nephrotic syndrome.

Disease Alternative Name

minimal change glomerulonephritis

nil disease

minimal change nephropathy

lipoid nephrosis

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Recent Cases of Minimal change disease

Browse recently discussed Minimal change disease cases by specialists

Concluded Case

Saurabh Burkul

MBBS Student

MINIMAL CHANGES DISEASE

10.2yrs /Boy No medical history Chief Complaints C/o :- Breathing difficulty , Puffy eye , Generalized Anacarsa ,Fatigue etc Physical Examination O/E:- S1 & S2 Normal B/L Crept On lower lobe of both lungs Investigations Ix 03/01/...See More

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Concluded answer

Dr. Dineshchandra Sharma

Endocrinology

It's nephrotic syndrome. Corticosteroids are the treatment of choice,that you are already administering, leading to complete remission of proteinuria in most cases. Approximately 90% of children respond within 2 weeks to prednisone at a do...

Concluded Case

Bhavya Arora

MBBS Student

Drugs causing Minimal Change Disease include 1) Interferon 2) Heroine 3) Probenecid 4) Pamidronate

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Concluded answer

Bhavya Arora

MBBS Student

Interferon.

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Top Cases of Minimal change disease

Selected by editors, top cases are known for unique problem or best solution

Dr. Ila Jain

Pathology

A previously healthy 20-year-old college student presents to the student health office complaining of a 1-week history of fatigue and dark-colored urine. On physical examination, his blood pressure is 155/90 mm Hg and his serum creatinine l...See More

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Dr. Ila Jain

Pathology

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